Deepak K. Dalvie: search on Z-Library

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1

Aldehyde Oxidase: An Enzyme of Emerging Importance in Drug Discovery

Pryde, David C., Dalvie, Deepak, Hu, Qiyue, Jones, Peter, Obach, R. Scott, Tran, Thien-Duc

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 4.29 MB

english, 2010

2

Aldehyde Oxidase and Its Role as a Drug Metabolizing Enzyme

Dalvie, Deepak, Di, Li

Journal:

Pharmacology & Therapeutics

Year:

2019

Language:

english

File:

PDF, 14.96 MB

english, 2019

3

Predicting Toxicities of Reactive Metabolite–Positive Drug Candidates

Kalgutkar, Amit S., Dalvie, Deepak

Journal:

Annual Review of Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.01 MB

english, 2015

4

Strategies for a comprehensive understanding of metabolism by aldehyde oxidase

Hutzler, James Matthew, Obach, Ronald Scott, Dalvie, Deepak, Zientek, Michael A

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Year:

2013

Language:

english

File:

PDF, 871 KB

english, 2013

5

Interactions of Nitrogen-Containing Xenobiotics with Monoamine Oxidase (MAO) Isozymes A and B: SAR Studies on MAO Substrates and Inhibitors

Kalgutkar, Amit S., Dalvie, Deepak K., Castagnoli,, Neal, Taylor, Timothy J.

Journal:

Chemical Research in Toxicology

Year:

2001

Language:

english

File:

PDF, 292 KB

english, 2001

6

Design, synthesis, and biological evaluation of novel 4-substituted 1-methyl-1,2,3,6-tetrahydropyridine analogs of MPTP

Zhao, Zhiyang, Dalvie, Deepak, Naiman, Noreen, Castagnoli, Kay, Castagnoli, Neal

Journal:

Journal of Medicinal Chemistry

Year:

1992

Language:

english

File:

PDF, 804 KB

english, 1992

7

Recent Advances in the Applications of Radioisotopes in Drug Metabolism,Toxicology and Pharmacokinetics

Journal:

Current Pharmaceutical Design

Year:

2000

Language:

english

File:

PDF, 245 KB

english, 2000

8

NADPH-Dependent Covalent Binding of [ 3 H]Paroxetine to Human Liver Microsomes and S-9 Fractions: Identification of an Electrophilic Quinone Metabolite of Paroxetine

Zhao, Sabrina X., Dalvie, Deepak K., Kelly, Joan M., Soglia, John R., Frederick, Kosea S., Smith, Evan B., Obach, R. Scott, Kalgutkar, Amit S.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 225 KB

english, 2007

9

Biotransformation and Bioactivation Reactions – 2016 Literature Highlights

Khojasteh, S. Cyrus, Rietjens, Ivonne M.C.M., Dalvie, Deepak, Miller, Grover

Journal:

Drug Metabolism Reviews

Year:

2017

Language:

english

File:

PDF, 1.24 MB

english, 2017

10

SAE Technical Paper Series [SAE International Symposium on International Automotive Technology 2013 - (JAN. 09, 2013)] SAE Technical Paper Series - Ultra Low PM, Naturally Aspirated Diesel Engine Development Meeting Off-Highway Tier IV (Final) Emission Norms

Bhosale, Sadanand, Rane, Santosh, Suresh, Rajendiran, S, Deepak, Atmaram, Dalvi, Patil, Ganesh

Year:

2013

Language:

english

File:

PDF, 4.02 MB

english, 2013

11

Characterization of the Selective Indoleamine 2,3-Dioxygenase-1 (IDO1) Catalytic Inhibitor EOS200271/PF-06840003 Supports IDO1 as a Critical Resistance Mechanism to PD-(L)1 Blockade Therapy

Gomes, Bruno, Driessens, Gregory, Bartlett, Derek, Cai, Danying, Cauwenberghs, Sandra, Crosignani, Stefano, Dalvie, Deepak, Denies, Sofie, Dillon, Christopher P, Fantin, Valeria R, Guo, Jie, Letellier

Journal:

Molecular Cancer Therapeutics

Year:

2018

Language:

english

File:

PDF, 3.26 MB

english, 2018

12

Reactive Drug Metabolites (KALGUTKAR:REACTIVE METAB. O-BK) || Pathways of Reactive Metabolite Formation with Toxicophores/-Structural Alerts

Kalgutkar, Amit S., Dalvie, Deepak, Obach, R. Scott, Smith, Dennis A.

Year:

2012

Language:

english

File:

PDF, 373 KB

english, 2012

13

Cytogenetic investigations in couples with repeated miscarriages and malformed children: report of a novel insertion

Priya Iyer, Leena Wani, Smruti Joshi, Jyothi Lakshmi, Rupa Dalvi, Deepak Chavan, Bibhu Ranjan Das, Swarna Mandava

Journal:

Reproductive BioMedicine Online

Year:

2007

Language:

english

File:

PDF, 534 KB

english, 2007

14

Assessment of Three Human in Vitro Systems in the Generation of Major Human Excretory and Circulating Metabolites

Dalvie, Deepak, Obach, R. Scott, Kang, Ping, Prakash, Chandra, Loi, Cho-Ming, Hurst, Susan, Nedderman, Angus, Goulet, Lance, Smith, Evan, Bu, Hai-Zhi, Smith, Dennis A.

Journal:

Chemical Research in Toxicology

Year:

2009

Language:

english

File:

PDF, 657 KB

english, 2009

15

Myeloperoxidase-mediated bioactivation of 5-hydroxythiabendazole: A possible mechanism of thiabendazole toxicity

Joseph D. Jamieson, Evan B. Smith, Deepak K. Dalvie, Gregory J. Stevens, Gina M. Yanochko

Journal:

Toxicology in Vitro

Year:

2011

Language:

english

File:

PDF, 511 KB

english, 2011

16

Pharmacokinetics and metabolism of single oral doses of trovafloxacin

John Vincent, Renli Teng, Deepak K. Dalvie, Hylar L. Friedman

Journal:

The American Journal of Surgery

Year:

1998

Language:

english

File:

PDF, 183 KB

english, 1998

17

Discovery of Potent, Non-Steroidal and Highly Selective Glucocorticoid Receptor Antagonists with Anti-Obesity Activity

Morgan, Bradley, Liu, Kevin, Dalvie, Deepak, Swick, Andrew, Hargrove, Diane, Wilson, Theresa, LaFlamme, Janet, Moynihan, Melinda, Rushing, Margaret, Woodworth, Graeme

Journal:

Letters in Drug Design & Discovery

Year:

2004

Language:

english

File:

PDF, 120 KB

english, 2004

18

Reactive Drug Metabolites (KALGUTKAR:REACTIVE METAB. O-BK) || Retrospective Analysis of Structure-Toxicity Relationships of Drugs

Kalgutkar, Amit S., Dalvie, Deepak, Obach, R. Scott, Smith, Dennis A.

Year:

2012

Language:

english

File:

PDF, 184 KB

english, 2012

19

Specific Chromosomal Aberrations in Primary Amenorrhoea: Study on 3776 Cases from Indian Population

Koppaka, Neeraja T., Virulkar, Shital K., Chavan, Deepak S., Dalvi, Rupa C., Gupta, Neelam, Mandava, Swarna

Journal:

The Journal of Obstetrics and Gynecology of India

Year:

2019

File:

PDF, 512 KB

2019

20

Design and Synthesis of Novel N-Hydroxy-Dihydronaphthyridinones as Potent and Orally Bioavailable HIV-1 Integrase Inhibitors

Hu, Qiyue, Kuehler, Jon E., Kuki, Atsuo, Johnson, Ted W., Tanis, Steven P., Butler, Scott L., Dalvie, Deepak, DeLisle, Dorothy M., Dress, Klaus R., Flahive, Erik J.

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 2.13 MB

english, 2011

21

Percutaneous transhepatic cholangioscopy with electrohydraulic lithotripsy in a patient with choledocholithiasis complicating a benign stricture

Hubers, Jeffrey, Patel, Ravi, Dalvie, Prasad, Megna, Bryant, Gopal, Deepak

Journal:

Year:

2019

Language:

english

File:

PDF, 845 KB

english, 2019

22

A Simple Litmus Test for Aldehyde Oxidase Metabolism of Heteroarenes

O’Hara, Fionn, Burns, Aaron C., Collins, Michael R., Dalvie, Deepak, Ornelas, Martha A., Vaz, Alfin D. N., Fujiwara, Yuta, Baran, Phil S.

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 1.17 MB

english, 2014

23

Cytogenetic profile of acute lymphocytic leukemia patients: report of a novel translocation t(4;13) (q21·3; q35) from an Indian population

Ahmad, Firoz, Dalvi, Rupa, Chavan, Deepak, Das, Bibhu Ranjan, Mandava, Swarna

Journal:

Hematology (American Society of Hematology)

Year:

2008

Language:

english

File:

PDF, 220 KB

english, 2008

24

A Comprehensive Listing of Bioactivation Pathways of Organic Functional Groups

Kalgutkar, Amit, Gardner, Iain, Obach, R., Shaffer, Christopher, Callegari, Ernesto, Henne, Kirk, Mutlib, Abdul, Dalvie, Deepak, Lee, Jae, Nakai, Yasuhiro, O'Donnell, John, Boer, Jason, Harriman, Shaw

Journal:

Current Drug Metabolism

Year:

2005

Language:

english

File:

PDF, 483 KB

english, 2005

25

Selection of optimum algae via wastewater combination

Chawla, Pushap, Malik, Anushree, Sreekrishnan, Trichur Ramaswamy, Dalvi, Vivek, Gola, Deepak

Journal:

Environmental Technology & Innovation

Year:

2020

Language:

english

File:

PDF, 1.98 MB

english, 2020

26

[Methods and Principles in Medicinal Chemistry] Reactive Drug Metabolites (KALGUTKAR:REACTIVE METAB.) || Origin and Historical Perspective on Reactive Metabolites

Kalgutkar, Amit S., Dalvie, Deepak, Obach, R. Scott, Smith, Dennis A.

Year:

2012

Language:

english

File:

PDF, 113 KB

english, 2012

27

Structure-based design, SAR analysis and antitumor activity of PI3K/mTOR dual inhibitors from 4-methylpyridopyrimidinone series

Cheng, Hengmiao, Hoffman, Jacqui E., Le, Phuong T., Pairish, Mason, Kania, Robert, Farrell, William, Bagrodia, Shubha, Yuan, Jing, Sun, Shaoxian, Zhang, Eric, Xiang, Cathy, Dalvie, Deepak, Rahavendran

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 1.03 MB

english, 2013

28

Effect of Intestinal Glucuronidation in Limiting Hepatic Exposure and Bioactivation of Raloxifene in Humans and Rats

Dalvie, Deepak, Kang, Ping, Zientek, Michael, Xiang, Cathie, Zhou, Sue, Obach, R. Scott

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 1.12 MB

english, 2008

29

[Methods and Principles in Medicinal Chemistry] Reactive Drug Metabolites (KALGUTKAR:REACTIVE METAB.) || Experimental Approaches to Reactive Metabolite Detection

Kalgutkar, Amit S., Dalvie, Deepak, Obach, R. Scott, Smith, Dennis A.

Year:

2012

Language:

english

File:

PDF, 189 KB

english, 2012

30

Biotransformation and bioactivation reactions – 2015 literature highlights

Baillie, Thomas A., Dalvie, Deepak, Rietjens, Ivonne M. C. M., Cyrus Khojasteh, S.

Journal:

Drug Metabolism Reviews

Year:

2016

Language:

english

File:

PDF, 2.57 MB

english, 2016

31

[Methods and Principles in Medicinal Chemistry] Reactive Drug Metabolites (KALGUTKAR:REACTIVE METAB.) || Case Studies on Eliminating/Reducing Reactive Metabolite Formation in Drug Discovery

Kalgutkar, Amit S., Dalvie, Deepak, Obach, R. Scott, Smith, Dennis A.

Year:

2012

Language:

english

File:

PDF, 570 KB

english, 2012

32

Characterization of polar urinary metabolites by ionspray tandem mass spectrometry following dansylation

Deepak K. Dalvie, John P. O’Donnell

Journal:

Rapid Communications in Mass Spectrometry

Year:

1998

Language:

english

File:

PDF, 94 KB

english, 1998

33

Drug discovery for a new generation of covalent drugs

Kalgutkar, Amit S, Dalvie, Deepak K

Journal:

Expert Opinion on Drug Discovery

Year:

2012

Language:

english

File:

PDF, 707 KB

english, 2012

34

Carbamates of (hydroxyphenoxy)methyl heteroaromatic salts as acetylcholinesterase inhibitors and protective agents against organophosphorus compounds

Sundberg, Richard J., Dalvie, Deepak, Cordero, Joehassin, Sabat, Michal, Musallam, H. A.

Journal:

Chemical Research in Toxicology

Year:

1993

Language:

english

File:

PDF, 726 KB

english, 1993

35

[Methods and Principles in Medicinal Chemistry] Reactive Drug Metabolites (KALGUTKAR:REACTIVE METAB.) || Mitigating Toxicity Risks with Affinity Labeling Drug Candidates

Kalgutkar, Amit S., Dalvie, Deepak, Obach, R. Scott, Smith, Dennis A.

Year:

2012

Language:

english

File:

PDF, 253 KB

english, 2012

36

Azaindole N-methyl hydroxamic acids as HIV-1 integrase inhibitors-II. The impact of physicochemical properties on ADME and PK

Steven P. Tanis, Michael B. Plewe, Ted W. Johnson, Scott L. Butler, Deepak Dalvie, Dorothy DeLisle, Klaus R. Dress, Qiyue Hu, Buwen Huang, Jon E. Kuehler, Atsuo Kuki, Wen Liu, Qinghai Peng, Graham L.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 1.54 MB

english, 2010

37

Synthesis of 4-(2-chloroethyl)-2,3-dihydro[1,4]oxazino[2,3-b]quinoline and 4-(2-chloroethyl)2,3-dihydropyrido[2,3-b][1,4]oxazine

Wayne K. Anderson, Deepak K. Dalvie

Journal:

Journal of Heterocyclic Chemistry

Year:

1993

File:

PDF, 293 KB

1993

38

[Methods and Principles in Medicinal Chemistry] Reactive Drug Metabolites (KALGUTKAR:REACTIVE METAB.) || Dealing with Reactive Metabolite-Positive Compounds in Drug Discovery

Kalgutkar, Amit S., Dalvie, Deepak, Obach, R. Scott, Smith, Dennis A.

Year:

2012

Language:

english

File:

PDF, 291 KB

english, 2012

39

Interspecies variation in the metabolism of zoniporide by aldehyde oxidase

Dalvie, Deepak, Xiang, Cathie, Kang, Ping, Zhou, Sue

Journal:

Year:

2013

Language:

english

File:

PDF, 1.33 MB

english, 2013

40

X-autosome translocations in amenorrhoea: a report of a three way translocation from Indian Population

Shetty, Dhanlaxmi L., Kadam, Akshay P., Koppaka, Neeraja T., Dalvi, Rupa C., Chavan, Deepak S., Das, Bibu R., Mandava, Swarna

Journal:

Gynecological Endocrinology

Year:

2014

Language:

english

File:

PDF, 480 KB

english, 2014

41

[Methods and Principles in Medicinal Chemistry] Reactive Drug Metabolites (KALGUTKAR:REACTIVE METAB.) || Managing IADRs - a Risk-Benefit Analysis

Kalgutkar, Amit S., Dalvie, Deepak, Obach, R. Scott, Smith, Dennis A.

Year:

2012

Language:

english

File:

PDF, 163 KB

english, 2012

42

Characterization of an unexpected product from a monoamine oxidase B generated 2,3-dihydropyridinium species

Dalvie, Deepak, Zhao, Zhiyang, Castagnoli, Neal

Journal:

Journal of Organic Chemistry

Year:

1992

Language:

english

File:

PDF, 543 KB

english, 1992

43

A Holistic Strategy for Characterizing the Safety of Metabolites through Drug Discovery and Development

Walker, Don, Brady, Joe, Dalvie, Deepak, Davis, John, Dowty, Martin, Duncan, J. Neil, Nedderman, Angus, Obach, R. Scott, Wright, Pat

Journal:

Chemical Research in Toxicology

Year:

2009

Language:

english

File:

PDF, 314 KB

english, 2009

44

Glucuronides as Potential Anionic Substrates of Human Cytochrome P450 2C8 (CYP2C8)

Ma, Yong, Fu, Yue, Khojasteh, S. Cyrus, Dalvie, Deepak, Zhang, Donglu

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 3.20 MB

english, 2017

45

[Methods and Principles in Medicinal Chemistry] Reactive Drug Metabolites (KALGUTKAR:REACTIVE METAB.) || Intrinsically Electrophilic Compounds as a Liability in Drug Discovery

Kalgutkar, Amit S., Dalvie, Deepak, Obach, R. Scott, Smith, Dennis A.

Year:

2012

Language:

english

File:

PDF, 242 KB

english, 2012

46

[Methods and Principles in Medicinal Chemistry] Reactive Drug Metabolites (KALGUTKAR:REACTIVE METAB.) || Role of Reactive Metabolites in Pharmacological Action

Kalgutkar, Amit S., Dalvie, Deepak, Obach, R. Scott, Smith, Dennis A.

Year:

2012

Language:

english

File:

PDF, 621 KB

english, 2012

47

Bioactivation of Lumiracoxib by Peroxidases and Human Liver Microsomes: Identification of Multiple Quinone Imine Intermediates and GSH Adducts

Kang, Ping, Dalvie, Deepak, Smith, Evan, Renner, Matt

Journal:

Chemical Research in Toxicology

Year:

2009

Language:

english

File:

PDF, 323 KB

english, 2009

48

[Methods and Principles in Medicinal Chemistry] Reactive Drug Metabolites (KALGUTKAR:REACTIVE METAB.) || Bioactivation and Natural Products

Kalgutkar, Amit S., Dalvie, Deepak, Obach, R. Scott, Smith, Dennis A.

Year:

2012

Language:

english

File:

PDF, 335 KB

english, 2012

49

Identification of primary and sequential bioactivation pathways of carbamazepine in human liver microsomes using liquid chromatography/tandem mass spectrometry

Hai-Zhi Bu, Ping Zhao, Deepak K. Dalvie, William F. Pool

Journal:

Rapid Communications in Mass Spectrometry

Year:

2007

Language:

english

File:

PDF, 332 KB

english, 2007

50

Pharmacokinetics and Metabolism of 2-Aminothiazoles with Antiprion Activity in Mice

Silber, B. Michael, Rao, Satish, Fife, Kimberly L., Gallardo-Godoy, Alejandra, Renslo, Adam R., Dalvie, Deepak K., Giles, Kurt, Freyman, Yevgeniy, Elepano, Manuel, Gever, Joel R., Li, Zhe, Jacobson, M

Journal:

Pharmaceutical Research

Year:

2013

Language:

english

File:

PDF, 1.18 MB

english, 2013

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